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Completed
NCT02812784
Can Nephrocheck™ Predict the Reversibility of Early, Acute Kidney Injury During Septic Shock?
Conditions: Heading
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 184
Sponsor: Centre Hospitalier Universitaire, Amiens
Location: CHU Amiens Amiens
Summary
Patients with septic shock in the intensive care unit have an elevated risk of developing acute kidney injury (AKI).
Eligibility Criteria
Inclusion Criteria:
* Age 18 or over
* Septic shock (according to Bone's criteria) within 4 hours of introduction of catecholamines
* AKI, characterized by a KDIGO score ≥ 1
* Social security coverage
Exclusion Criteria:
* AKI requiring emergency RRT (in the critical care physician's opinion).
* Anuria
* Stage 4-5 chronic kidney failure with a GFR below 30 ml/min.
* Rapidly progressing renal disorders (glomerulonephritis, HUS, blockage, etc.)
* Obstructive AKI
* Probable glomerular damage (nephritic syndrome, nephrotic syndrome, chronic glomerulonephritis)
* Pregnancy or breastfeeding
* Legal guardianship or lack of social security coverage.
* Cardiocirculatory arrest
* Life expectancy \
Source: ClinicalTrials.gov (NCT02812784). StuddyBuddy aggregates publicly available trial information.