Timing of Rectal Cancer Resection After Preoperative Chemoradiotherapy

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 50

Sponsor: Health Sciences North Research Institute

Summary

This pilot study will take place at Health Sciences North (HSN) in Sudbury. Patients will be identified and screened for inclusion into the study once referred to a general or colorectal surgeon for resection of their rectal cancer. This may occur before or after preoperative chemoradiotherapy (CRT) but randomization will take place after CRT.

Eligibility Criteria

Inclusion Criteria: * Adult patients (\>18 years) * T3/4N0M0 or TxN+M0 rectal cancer below or at the peritoneal reflection, confirmed on clinical exam, histology, pelvic MRI, and CT chest/abdo * Patients who have completed a CRT protocol for the above tumor at HSN * Informed consent given * Surgical resection with TME planned Exclusion Criteria: * Metastatic disease * Failure to complete preoperative CRT * Unable to give free and informed consent * Unable to comply with the requirements of the study * Previous malignancy other than nonmelanoma skin cancer, papillary or follicular thyroid cancer * Inflammatory bowel disease * Hereditary colorectal cancer

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT02441153). StuddyBuddy aggregates publicly available trial information.