← Back to all trials
Recruiting
NCT02426398
Developing a New EEG Method for the Early Diagnosis of Dementia
Conditions: Dementia
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Enrollment: 128
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust
Location: Sheffield Teaching Hospitals NHS Trust Sheffield S Yorks
Summary
This is a non-invasive study investigating whether EEG, which is used in routine clinical care can be useful in diagnosing dementia. Novel in house developed software will analyse EEG data for this purpose from people with Alzheimer's disease and healthy volunteers.
Eligibility Criteria
Inclusion Criteria:
• Clinical diagnosis of possible or probable AD (according to revised diagnostic criteria (McKhann et al., 2011, Dubois et al., 2007)
Exclusion Criteria:
* Significant vascular change on neuro-imaging (Fazekas grading of white matter change \>2) (Fazekas et al., 2002).
* Clinical history of stroke, Parkinsonism, epilepsy or other neurological disorder. (e.g. severe auditory, visual, language or motor impairment)
* Moderate to severe dementia (defined by research team but we wouldn't expect those with a mini mental state exam \[MMSE\] ≤ 18 to be able to participate)
* Severe current mental health disorder (depression, psychosis).
* Patients on sedating or antiepileptic medication
Source: ClinicalTrials.gov (NCT02426398). StuddyBuddy aggregates publicly available trial information.