The Kabeho Study: Kigali Antiretroviral and Breastfeeding Assessment for the Elimination of HIV

The study design includes an observational prospective cohort of HIV-positive pregnant/postpartum women and their infants enrolled during antenatal clinics (or immediately postpartum) from prevention of mother-to-child transmission (PMTCT) programs and followed until the infants reach the age of 18 - 24 months and semi-structure interviews with a sub-set of these women. A second study component involves semi-structured interviews with health care workers (HCW) involved in the PMTCT programs and yearly facility surveys at the selected study facilities.

Inclusion Criteria: * Documented HIV infection * Pregnant, in the last trimester of pregnancy or within two weeks post-delivery. * Participation in the PMTCT program during antenatal care at one of the study sites * Planning on remaining in the Kigali area after delivery * Able and willing to give informed consent for study participation for herself and her infant(s). If a pregnant woman is less than 18 years of age and still living with her parents, informed consent will also be required from one of her parents Exclusion Criteria: * Women not willing to provide informed consent to participate