Proof of Concept of an Anaplerotic Study Using Brain Phosphorus Magnetic Resonance Spectroscopy in Huntington Disease

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Phase: PHASE2

Enrollment: 10

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Summary

The purpose of this project is to study the efficacy of an anaplerotic treatment on brain energy profile evolution at an early stage of the Huntington disease.

Eligibility Criteria

Inclusion Criteria: * 5 \< UHDRS \< 50 * Age \> 18 years * Ability to undergo MR scanning * Covered by french social security Exclusion Criteria: * Evidence of psychiatric disorder * Attendant neurological disorder * Contraindications to MRI (claustrophobia, metallic or material implants) * Severe head injury * Unable to understand the protocol * Pregnancy * Failure to give informed consent * Subjects with exclusion criteria required by french law (e.g. subjects who require a legally authorized representative to obtain consent) * Unwillingness to be informed in case of abnormal MRI

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT01882062). StuddyBuddy aggregates publicly available trial information.