Determinants of Cognitive Impairment After Acute Coronary Syndrome

The general purpose of the present pathophysiological study is to investigate the relation between cognitive impairment observed after an acute coronary syndrome and the presence of cerebral anatomo-functional abnormalities. This study will improve the investigators' understanding of the disease and will help in early diagnosis and prevention of vascular dementia in this population.

Inclusion Criteria: * Male and female * Age :30 to 65 years * First acute coronary syndrome occurred 4 ± 1 months before the inclusion * Able to understand the use of a pocket computer (palm) * Able to use a pocket computer (palm) * Able to give informed consent * Affiliated to social insurance Exclusion Criteria: * Past medical history of stroke * Diamox® injection contraindication * Dementia * History of major depression * Aphasia * Severe visual deficiency * Contra-indication to brain MRI * Contra-indication to HMPAO * Contra-indication to Acetazolamide * Patient under safeguard of justice * For women, ineffective contraceptive method * Breast-feeding or Pregnant women