The Method ISET (Insulation by Size of Epithelial Tumor Cells)

The aim of this study is, i) to assess the presence and the frequency of CTC in NSCLC patients undergoing surgery by using cytopathological analysis after their isolation by size (ISET method), and, ii) to correlate the presence of CNHC with pTNM stage, histological subtype, and percentage of tumor cells present into the primary tumors.

Inclusion Criteria: For the patients: * patient having been operated for a strong suspicion or a suspicion of a malignant tumoral hurt corresponding to a primitive carcinoma not in small cell of the lung For the control subjects: * Tabagical patients (between 10 and 30 packages years) * unhurt of any malignant or mild tumoral pathology or patients that must benefit from a surgical operation for an extract of a hurt lung parenchymateuse for a not tumoral hurt Exclusion Criteria: * Patient with histories of cancer or the other synchronous cancer * Patient with carcinomas with small cells, bronchiolo-alveolar carcinomas, the other types of tumors (lymphomes, sarcomas, etc.). * Patient with neoadditives treatments * Patient according to treatments additives others than protocols codified (in particular, platinum navelbine or gemcitabine platinum) for stages II