Functional Magnetic Resonance Imaging - Synthetic Aperture Magnetometry (fMRI-SAM) and Alzheimer's Disease

Sex: All

Ages: 55 Years – 75 Years

Healthy volunteers: Yes

Phase: NA

Sponsor: University Hospital, Strasbourg, France

Summary

The aim of the protocol is to study the resting brain activation profile of 3 groups of people, using a new fMRI procedure, called fMRI-SAM. fMRI-SAM will be applied to 25 Alzheimer's disease (AD) patients, 25 patients suffering from amnestic - mild cognitive impairment (MCI) - a clinical picture which may be a prodromal form of AD - and 60 healthy controls. The first analysis of the data will search differences of brain activation profiles between the 3 groups. In the second step, the investigators will study the predictive value of fMRI-SAM to detect MCI patients who will later convert to AD.

Eligibility Criteria

Inclusion criteria: * Alzheimer's disease of mild to moderate severity (25 patients) * Amnestic MCI patients (25 patients) * 55-75 year-old patients Exclusion criteria: * Any other cause of dementia for AD patients * Any stroke * Any disease with a negative vital prognosis

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT00412048). StuddyBuddy aggregates publicly available trial information.