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Completed
NCT00081874
RAD001 in Relapsed or Refractory AML, ALL, CML in Blastic-Phase, Agnogenic Myeloid Metaplasia, CLL, T-Cell Leukemia, or Mantle Cell Lymphoma
Conditions: Leukemia, Mantle Cell Lymphoma, Myelofibrosis
Sex: All
Healthy volunteers: No
Phase: PHASE1, PHASE2
Enrollment: 29
Sponsor: M.D. Anderson Cancer Center
Location: M.D. Anderson Cancer Center Houston Texas
Summary
The goal of this clinical research study is to find the highest safe dose of RAD001 that can be given as a treatment for leukemia, mantle cell lymphoma, or myelofibrosis. Another goal is to learn how effective the dose that is found is as a treatment.
Eligibility Criteria
Inclusion Criteria:
1. Patients with advanced, relapsed or refractory: acute leukemias (AML, ALL), MDS, CMML in transformation with greater than or equal to 10% peripheral blood/bone marrow blasts, CML in blastic phase, agnogenic myeloid metaplasia (AMM), CLL, T-cell leukemia, or mantle cell lymphoma.
2. Serum bilirubin \
Source: ClinicalTrials.gov (NCT00081874). StuddyBuddy aggregates publicly available trial information.